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Metabolism Diazepam is N-demethylated by CYP3A4 and 2C19 to the Energetic metabolite N-desmethyldiazepam, and is hydroxylated by CYP3A4 to the Lively metabolite temazepam.I have experienced a grandmal seizure and wound up in healthcare facility ,i have found diazapam incredibly handy with stopping any more seizures also i put up with pms and acquir